["python","pandas"]
Pandas replace a character in all column names

I have data frames with column names (coming from .csv files) containing ( and ) and I'd like to replace them with _. How can I do that in place for all columns?
Use str.replace: df.columns = df.columns.str.replace("[()]", "_", regex=True) Sample: df = pd.DataFrame({'(A)':[1,2,3], '(B)':[4,5,6], 'C)':[7,8,9]}) print (df) (A) (B) C) 0 1 4 7 1 2 5 8 2 3 6 9 df.columns = df.columns.str.replace(r"[()]", "_", regex=True) print (df) _A_ _B_ C_ 0 1 4 7 1 2 5 8 2 3 6 9